In the early 1990s, the National Institutes
of Health set up to investigate a few crucial issues of Women’s Health Initiative (WHI), a collection of studies that
would cost in the neighbourhood of a billion dollars. Among the questions that
the researchers hoped to answer was even if low-fat diets actually prevent
heart disease or cancer, at least in women. So they enrolled nearly 50 000
women in a trial, chose 20 000 at random, and instructed them to eat a low-fat
diet, rich in fruits, vegetables, and fiber. These women were given regular
counselling to motivate them to stay on the diet.
One of the effects of this counseling, or maybe of the diet itself, is
that the women also decided, consciously or unconsciously, to eat less.
According to the WHI researchers, the women, on average, consumed 360 calories
a day less on their diets than they did when they first agreed to participate.
If we believe that overeating causes obesity, we might say that these women
were “under eating” by 360 calories a day. They were eating almost 20% fewer
calories than what public-health agencies tell us such women should be eating.
The result? After 8 years of such under eating, these women lost an
average of 2 pounds each. And their average waist circumference–a measure of
abdominal fat–increased. This suggests that whatever weight these women lost,
if they did was not fat but lean tissue–muscle.
This wasn’t the only disappointing result in the study. The WHI
investigators also reported that the low–fat diet failed to prevent heart
disease, cancer, or anything else.
This calculation is oversimplified to make a point. If it is corrected
for the observation that subjects who lose weight in diets expend less energy
as they do it, then the amount of weight loss expected with this energy deficit
should be less” approximately 1.6 pounds at 3 weeks and 22 pounds at 1 year. I
owe this correction to Kevin Hall, a Biophysicist at NIH, who points out that
the corrected numbers are “still a far cry from the observed value!”
Although Stunkard’s analysis has widely been perceived as a condemnation
of all methods of dietary treatment of obesity, the studies he reviewed
included only calories-restricted diets.
I
don’t count the WHI low-fat diet trial, because that was aimed at preventing
heart disease and cancer, not losing weight.




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